Omega-3 Fatty Acids and Autoimmune Disease

eat intelligently

Anyone who thinks that diet is not important when it comes to chronic diseases is very sadly misinformed.

Autoimmune diseases are triggered by environmental factors, what more of an influential factor than the food that we put into our bodies on a daily basis and ofcourse the air we breathe?!

Our food chain has become so tampered with that half the time we do not even know what were are eating (you only need to look at the latest scandal regarding the horsemeat).  Foods have been processed for longevity on our supermarket shelves and for added “taste” and to “look good”  to the point where nutritional factor has been severely compromised.

This is a fantastic read and it is fairly lay so hopefully your eyes wont glaze over!  Many autoimmune conditions can be managed through dietary choices, I would rather manage my autoimmune with diet than with steroids.

I am going to give those of you who are interested in factual information regarding diet and chronic low grade inflammation this review to read.  Diet is an amazing way to manage autoimmune diseases and we need to be more informed of researach like this.


Among the fatty acids, it is the omega-3 polyunsaturated fatty acids (PUFA) which possess the most potent immunomodulatory activities, and among the omega-3 PUFA, those from fish oil—eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)—are more biologically potent than-linolenic acid (ALA).  Some of the effects of omega-3 PUFA are brought about by modulation of the amount and types of eicosanoids made, andother effects are elicited by eicosanoid-independent mechanisms, including actions upon intracellular signaling pathways, transcription factor activity and gene expression. Animal experiments and clinical intervention studiesindicate that omega-3 fatty acids have anti-inflammatory properties and, therefore, might be useful in the management of inflammatory and autoimmune diseases. Coronary heart disease, major depression, aging and cancer are characterized by an increased level of interleukin 1 (IL-1), a proinflammatory cytokine. Similarly, arthritis, Crohn’s disease, ulcerative colitis and lupus erythematosis are autoimmune diseases characterized by a high level of IL-1 and the proinflammatory leukotriene LTB 4 produced by omega – 6 fatty acids.  There have been a number of clinical trials assessing the benefits of dietary supplementation with fish oils in several inflammatory and autoimmune diseases in humans, including rheumatoid arthritis, Crohn’s disease, ulcerative colitis, psoriasis, lupus erythematosus, multiple sclerosis and migraine headaches. Many of the placebocontrolled trials of fish oil in chronic inflammatory diseases reveal significant benefit, including decreaseddisease activity and a lowered use of anti-inflammatory drugs.

omega 3

Excellent food sources of Omega 3 Fatty acids are

  • Sardines
  • Eggs
  • Salmon
  • Flax seeds
  • Walnuts

Thank you for reading and please to all my followers can you click on to our new charity website Autoimmune Alopecia Research UK and sign up if you are a sufferer of Autoimmune Alopecia.  This will be very important for research in the future plus we can keep you up to date with all the latest news and events.

Thanks for reading guys

Jayne xxx

11 thoughts on “Omega-3 Fatty Acids and Autoimmune Disease

  1. i have alopecia doctor says it is areta alopecia. 4 big patches on the back of my head. how much fish oils should i take every day and what brand of fish oils jane. thanks tania xxx

    • Hi Tania,

      Fish oils alone will not help. They aim to decrease the inflammatory response in the body but they will be of no use if you are still eting foods that are causing an inflammatory response.
      If I were you I would look at my diet. I would try to cut out possible trigger foods. Main culprits being wheat , gluten and dairy. I would stock up on eating oily fish and green leafy vegetables and fruit and totally cut out processed sugars if possible. Supplement with a good fish oil capsule I take 1 tab twice a day (remember you are getting oils from natural food sources too) and take a multi vitamin.

      Please look at the new research site and sign up for latest news… we shall be talking about things like this on there as we progress.

      All the best

      Jayne x

      • Inflammation occurs in the body in response to a cut or a graze or an invasion of a bacteria or other pathogen. Our bodies immune cells (good cells) all swarm to the area where there is infection to get to work to kill the foreign body and mop up the debris and drain it through our lymphatic system. Teh inflammatory response is therefore our bodies healing mechanism.. In autoimmune disease there is an inflammatory response occuring in the body on a daily basis. Now we do not know why this response is occuring as there is no evidence to suggest and invasion of a bacteria or pathogen of any sort, but something is triggering this response around our hair follicles. The healing cells and busy working away attacking healthy tissue cells by mistake. Therefore there is this low grade inflammatory response going on continually. There is obviously a much more complex mechanism involved but that is me trying to put it in lay terms. I hope this helps!
        Jayne x

  2. i have lupus also and doctors never told me fish oils would be better than prednislone and can manage autoimmune like lupus. i hate pred because of side effects can i take the fish oils instead of the preds ??. i only eat vegetables and chicken no horsemeat for me yuk.

    • That is a choice that only you can make. I cannot help you make that decision and something that you may wish to talk over with your doctor. Diet is very powerful and to be honest most doctors are not going to back you up on that decision. The way I look at it is…. it is your body and I would do my research into other people who have lupus and talk with people who have had possible relief from diet. I know people who suffer MS who have come of meds and stuck to a really strict diet and it has manages their symptoms. You have to find what works for you AND it is not easy so you need to assess whether your lifestyle will cope with such a change in diet. I do not know much about lupus so it is hard for me to comment but diet is overlooked in far too many autoimmune diseases.

      All the best Tan

      Jayne x

  3. Ahh okay, i think i understand. so i need to stop eating the food that is making the inflammtory responses and alopecia so no more is made. then use fish oil to drain away the leftover inflammatory response. then i need to keep not eating the bad food so the inflammatory response doesnt come back and make my follicles fall out again. have i got that right jane, this is complicated stuff. thanks again tania xxx

  4. I do not even know how I ended up here, but I thought this post was good.
    I do not know who you are but certainly you’re going
    to a famous blogger if you aren’t already 😉 Cheers!

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